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Case studies in cardiovascular nursing
The impact of carvedilol on the defibrillation threshold
Heart & Lung: The Journal of Cardiopulmonary and Acute Care
Vol. 37Issue 1p67–71Published in issue: January, 2008
- Brian F. McBride
- C. Michael White
- James S. Kalus
- Danette C. Guertin
- Christopher A. Clyne
- William L. Baker
- and others
Cited in Scopus: 4
Defibrillation threshold (DFT) is the minimum energy required to successfully terminate ventricular fibrillation. Epinephrine has been shown to increase the DFT in the beta-blocker naïve, but using cardioselective beta-blockers leads to a reduction in the DFT on infusion of epinephrine and norepinephrine. We sought to determine the impact of carvedilol therapy on the DFT after infusion of epinephrine and norepinephrine.