Dear Editor, we would like to share ideas on the publication “The association of IL-10-1082G/A
gene polymorphism with the risk of acute lung injury/respiratory distress syndrome
(ALI/RDS): A meta-analysis.1” In order to determine the early warning signs of ALI/RDS, Yao et al. used the meta-analysis
approach to clarify the association between SNP at the IL-10-1082G/A gene and susceptibility
to ALI/RDS.
1
Yao et al. came to the conclusion that SNP at the IL-10-1082G/A locus increased the
risk of ALI/RDS, with genotype GG and allele G increasing the risk, particularly in
Asia.
1
In addition to allele G, genotypes GG+GA, GG, and GA at the IL-10-1082G/A gene have
been linked to increased vulnerability to NRDS,
1
according to Ya et al. We both concur that the SNPs under investigation could influence
cancer risk. It is important to consider the possibility of other complicating circumstances.
Some additional genetic variations may have confused the results of the current investigation,
although Yao et al. did not examine them.To read this article in full you will need to make a payment
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References
- The association of IL-10-1082G/A gene polymorphism with the risk of acute lung injury/respiratory distress syndrome (ALI/RDS): A meta-analysis.Heart Lung. 2022 Dec 13; 58: 158-165
- Association between insertion/deletion polymorphism in angiotensin-converting enzyme gene and acute lung injury/acute respiratory distress syndrome: a meta-analysis.BMC Med Genet. 2012 Aug 31; 13: 76
- -308GA and TNFB polymorphisms in acute respiratory distress syndrome.Eur Respir J. 2005 Sep; 26: 382-389
Article info
Publication history
Published online: December 30, 2022
Accepted:
December 20,
2022
Received:
December 18,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
