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Research Article| Volume 58, P134-138, March 2023

Independent predictors and equation of six-minute walk test in post-cardiac surgery

Published:December 09, 2022DOI:https://doi.org/10.1016/j.hrtlng.2022.12.002

      Highlights

      • This is the first study to compare 6MWD between at hospital discharge and the 4–6-week follow-up after cardiac surgery.
      • 6MWD at discharge, regular exercise, age, gender, and NYHA classification were found to independently predict 6MWD at 4–6 weeks after hospital discharge.
      • The equation generated by multivariate analysis to predict 6MWD recovery after hospital discharge.

      Abstract

      Background

      The six-minute walk test (6MWT) has been used to evaluate postsurgical recovery in cardiac patients. No previous study has compared the 6MWT at follow-up with a baseline, or evaluated the long-term effects of cardiac surgery on post-discharge 6MWT

      Objectives

      To identify the factors independently associated with 6MWD, and to develop an equation to predict 6MWT at the 4–6-week follow-up after post-cardiac surgery hospital discharge.

      Methods

      Patient data of elective coronary artery bypass graft (CABG) or non-CABG surgery patients were retrospectively collected. The 6MWT was performed at hospital discharge and at the 4–6-week follow-up. Available demographic and clinical data of patients were analyzed to determine the independent factors of 6MWT. An equation to predict 6MWT were generated by forward stepwise multiple linear regression analysis.

      Results

      The data of 275 patients (mean age: 62.20±14.57 years, 64.7% male) were analyzed. The mean 6MWT was 179.14±92.18 m at discharge, and increased to 335.20±115.51 m at the 4–6-week follow-up. The 6MWT at the 4–6-week follow-up was independently correlated with 6MWT at discharge, regular exercise, age, gender, and preoperative New York Heart Association (NYHA) classification.

      Conclusion

      The independent predictors: 6MWT at discharge, regular exercise, age, gender, and NYHA classification were used to generate an equation to predict 6MWT at 4–6 weeks after hospital discharge.

      Keywords

      Abbreviations:

      6MWT (six-minute walk test), CABG (coronary artery bypass graft), NYHA (New York Heart Association), BMI (body mass index), DM (diabetes mellitus), HT (hypertension), DLP (dyslipidemia), CKD (chronic kidney disease), AF (atrial fibrillation), EF (ejection fraction), LOS (length of hospital stay)
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