Highlights
- •A questionnaire was developed, and psychometric properties were tested.
- •It showed acceptable properties in internal consistency, test-retest reliability, and construct validity.
- •It may be a useful tool for communication between patients and health care practitioners.
Abstract
Background
Fatigue and breathlessness are the two most common and distressing symptoms for patients
with chronic heart failure. They affect a patient's quality of life and ability to
undertake activities of daily living. Currently there are no symptom specific measures
for fatigue and breathlessness available or developed and validated for use with this
patient group and no questionnaire that incorporates both symptoms into one measure.
Objective
To develop a patient-reported outcome measure for patients with chronic heart failure
for their fatigue and breathlessness symptoms.
Methods
A three-staged, approach was used. In stage One in-depth qualitative patient-interviews
on factors of fatigue and breathlessness in chronic heart failure were undertaken
to provide question themes. Items from these interviews were generated and pilot questionnaires
developed and tested. In Stage Two, exploratory factor analysis with item reduction
and final testing of the questionnaire was performed. Stage Three involved validation
testing.
Results
In Stage One, issues raised in interviews (n = 25) were used to generate items. Pilot questionnaires were developed and tested.
Items were refined in the context of cognitive debrief interviews (n = 7) for possible inclusion in the final measure. Final testing of questionnaire
properties with item reduction was carried out in Stage Two (n = 112). Validity and reliability were assessed in Stage Three (n = 96). Psychometric testing showed positive results, in internal consistency (Cronbach's
alpha ranging from 0.8 to 0.94) and test-retest (no difference in means), content
validity and relevance to patients.
Conclusions
This questionnaire could be useful in the assessment of fatigue and breathlessness
in patients living with chronic heart failure.
Keywords
Abbreviations:
CHF (Chronic Heart Failure), DFI (Feinstein Dyspnoea and Fatigue Index), EPR (Electronic Patient Record), EFA (Exploratory Factor Analysis), ESC (European Society of Cardiology), FDA (Food and Drug Administration), HF-rEF (Heart Failure with reduced Ejection Fraction), ICC (Intraclass Correlation Coefficient), KCCQ (Kansas City Cardiomyopathy Questionnaire), MLHFQ (Minnesota Living with Heart Failure Questionnaire), OxFAB (Oxford Fatigue and Breathlessness Questionnaire), PCA (Principal Component Analysis), PROM (Patient-reported Outcome Measure), SPSS (Statistical Package for the Social Sciences), TA (Translatability Assessment)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 06, 2022
Accepted:
November 29,
2022
Received in revised form:
November 28,
2022
Received:
June 14,
2022
Identification
Copyright
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