Highlights
- •The mean BMI (Body Mass Index) for our cohort was 31.1 kg/m2 (SD 8 kg/m2).
- •BMI for patients that survived compared to those that did not was 29.7 kg/m2 vs. 33.7 kg/m2 (p = 0.04).
- •Incremental increase in obesity classification was associated with a 1.6 (95% CI 1.1 – 2.6, p = 0.03) odds of mortality.
Abstract (222/250)
Introduction
Cardiogenic shock (CS) is associated with high mortality despite the development of
risk stratification tools and new treatment strategies. Obesity, although a risk factor
for cardiovascular disease, is not included in current risk stratification tools for
CS. A relationship between mortality and obesity has only been shown in subsets populations
of CS; there is not yet a clear relationship between severity of obesity and all-cause
CS.
Objectives
In this study we evaluate the relationship between rising body mass index (BMI) and
mortality in all-cause CS. Methods: All patients with BMI measurements and hospitalizations
complicated by CS from 2014 to 2019 at a single quaternary care institution were identified.
Patients were grouped by obesity classification. Multivariate logistic regression
was performed to determine a relationship between higher obesity classifications with
30-day mortality in patients with CS.
Results
Seventy-two patients were available for analysis. Mean BMI for those who survived
compared to those who did not was 29.7 ± 8 kg/m2 vs 33.7 ± 7.6 kg/m2 (p = 0.04). The odds ratio for mortality with incremental increase in obesity classification
was 1.6 (95% CI 1.1 – 2.6, p = 0.03) after adjusting for etiology of CS and other common associations with CS
mortality.
Conclusion
This study suggests that the higher mortality risk with incremental increases in BMI
should be taken into account when risk stratifying these patients.
Keywords
Abbreviation:
CS (cardiogenic shock), BMI (body mass index), UW (underweight), NW (normal weight), OW (overweight), OB (obese), C1O (Class I Obesity), C2O (Class II Obesity), C3O (Class III Obesity), CPI (cardiac power index), PAPi (pulmonary artery pulsatility index)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: September 06, 2022
Accepted:
August 28,
2022
Received in revised form:
August 13,
2022
Received:
May 1,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
