Highlights
- •Inspiratory training increases MIP in PH.
- •Inspiratory training does not improve functional capacity, PA, and QoL in PH.
- •Inspiratory training is a safety rehabilitation technique for PH.
Abstract
Background
Impaired respiratory muscle function may be one of the causes of increased dyspnea,
reduced exercise capacity, and physical activity (PA), and poor quality of life in
pulmonary hypertension (PH).
Objective
To investigate the effects of threshold inspiratory muscle training (TIMT) on respiratory
functions, functional exercise capacity, PA, and QoL in patients with PH.
Methods
Thirty patients with PH were randomly allocated to a TIMT (n = 15) and sham group (n = 15). Three patients in the sham group could not participate in the program. The TIMT
group (n = 15) trained at 30% of the maximal inspiratory pressure (MIP), and the sham group
(n = 12) performed at lowest pressure without change in threshold pressure. In both groups,
patients performed TIMT at home for 15 min, twice per day, with the MIP load determined
by the trainer, and were supervised once weekly at the hospital for eight weeks. The
primary outcomes were MIP and maximal expiratory pressure (MEP). The secondary outcome
measures included spirometric measurements, six-minute walking distance (6MWD), PA
(SenseWear armband and International Physical Activity Questionnaire-Short Form-IPAQ-Short
Form), and QoL (Minnesota Living with Heart Failure-MLHF).
Results
After the training, changes in MIP (p = 0.023) were higher in the intervention group compared with the sham group. Differences
in MEP, FEV1 (%), FVC (%), FEV1/FVC (%), 6MWD, %6MWD, IPAQ-SF, MLHFQ, and armband
parameters were not significantly different between the groups (p > 0.05).
Conclusions
The results of the study demonstrated that TIMT could increase MIP and did not improve
other parameters of respiratory functions, functional exercise capacity, PA, and QoL
in patients with PH.
Keywords
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Article info
Publication history
Published online: March 04, 2020
Accepted:
January 6,
2020
Received in revised form:
January 6,
2020
Received:
July 19,
2019
Identification
Copyright
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