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Research Article| Volume 49, ISSUE 4, P415-419, July 2020

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Performance of quick sequential organ failure assessment (qSOFA) score for prognosis of heat-related hospitalized patients

      Highlights

      • Heat-related illnesses pose significant threats to human health.
      • qSOFA score can be used as a parameter to distinguish severe hospitalized patients.
      • Multiple organ impairment should be considered when assessing patient prognosis.

      Abstract

      Background

      Heat-related illnesses pose significant threats to human health.

      Objectives

      (1) To evaluate the use of qSOFA score for prognosis of heat-related hospitalized patients; and (2) identify other predictors for patient prognosis.

      Methods

      Using 28-day mortality as the primary endpoint, a retrospective, observational study of patients hospitalized between June 2013 and September 2018 was conducted.

      Results

      The qSOFA score from 84 patients was identified as an independent predictor of patient prognosis. The area under the receiver operating characteristic curves for qSOFA score was 0.702, and a sensitivity of 100.00% and a specificity of 47.06% were found for qSOFA score greater than or equal to 2. Other predictors included bilirubin, urea nitrogen, and troponin I levels.

      Conclusions

      qSOFA score can be used as a parameter to distinguish patients with severe heat-related illness prior to further clinical analyses. In addition to that, multiple organ impairment should be considered when assessing patient prognosis.

      Keywords

      Abbreviations:

      HS (heat stroke), ICU (intensive care unit), qSOFA (Quick Sequential Organ Failure Assessment), SOFA score (sequential organ failure assessment score), ALT (alanine transaminase), AST (aspartate transaminase), TB (total bilirubin), CK (creatinine kinase), BUN (blood urea nitrogen), Cr (creatinine), WBC (white blood cell count), Hb (hemoglobin), PLT (platelet count), INR (international normalized ratio), TnI (troponin I), ROC curves (Receiver operating characteristic curves), AUROC (Area under the receiver operating characteristic curves)
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