Highlights
- •There is a decreasing trend in hospital admissions among young adults with atrial fibrillation.
- •The frequency of hypertension, diabetes and obesity among young adults admitted with atrial fibrillation nearly doubled from 2005 to 2015.
- •There was also a marked increase in the frequency of obstructive sleep apnea, alcohol abuse and drug abuse among patients admitted with atrial fibrillation.
- •In the last decade there has been a substantial rise in the cardiovascular risk in the cardiovascular risk factors among young.
- •There was an increase in the mean cost of hospitalization from 2005 to 2015.
Abstract
Introduction
Atrial fibrillation is the most frequently occurring and studied arrhythmia. There
is a limited data on young patients presenting with atrial fibrillation.
Objective
The objective of this research article was to assess the trend of hospitalization,
epidemiological characteristics and economic burden in the young adult, aged 18–45
years, presenting with atrial fibrillation.
Methods
Hospitalization data from the National Inpatient Sample between 2005 and 2015 were
used to analyze prevalence of risk factors and financial burden in young adults with
atrial fibrillation.
Results
From 2005 to 2015, a total of 260,080 admissions were included in the study. From
2005 to 2015, there was a decreasing trend of total admissions with atrial fibrillation
among the age group of 18–45 years compared to total admissions due to atrial fibrillation
and total population. However, there was an increasing trend of admission observed
in young females, white and black population. The frequency of hypertension, diabetes
and obesity among young adults admitted with atrial fibrillation nearly doubled from
2005 to 2015. There was also a marked increase in the frequency of obstructive sleep
apnea, alcohol abuse and drug abuse among patients admitted with atrial fibrillation.
Furthermore, there was an increase in the mean cost of hospitalization from $7363
in 2005 to $7924 in 2015, Ptrend < 0.001.
Conclusion
In conclusion, increased cardiovascular risk factors among young adult with admissions
for atrial fibrillation warrants controlling of the risk factors to further curtail
hospitalizations.
Keywords
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Reference
- Frequency of cardiac rhythm abnormalities in a half million adults.Circ Arrhythmia Electrophysiol. 2018; 11e006273https://doi.org/10.1161/CIRCEP.118.006273
- Secular trends in incidence of atrial fibrillation in olmsted county, minnesota, 1980 to 2000, and implications on the projections for future prevalence.Circulation. 2006; 114: 119-125https://doi.org/10.1161/CIRCULATIONAHA.105.595140
- Assessing the direct costs of treating nonvalvular atrial fibrillation in the united states.Value Heal. 2006; 9: 348-356https://doi.org/10.1111/j.1524-4733.2006.00124.x
- Atrial fibrillation in young patients.Expert Rev Cardiovasc Ther. 2018; 16: 489-500https://doi.org/10.1080/14779072.2018.1490644
- Evaluation of the incidence of new-onset atrial fibrillation after aortic valve replacement.JAMA Intern Med. 2019; 179: 1122-1130https://doi.org/10.1001/jamainternmed.2019.0205
- In-Hospital management and outcomes after ST-segment-elevation myocardial infarction in medicaid beneficiaries compared with privately insured individuals.Circ Cardiovasc Qual Outcomes. 2019; 12e004971https://doi.org/10.1161/CIRCOUTCOMES.118.004971
- Healthcare Cost and Utilization Project. 30. Agency for Healthcare Research and Quality, 2019 (HCUP methods series)
- Adherence to methodological standards in research using the national inpatient sample.JAMA. 2017; 318 (2011–2018)
- 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation.Circulation. 2014; 130: e199-e267https://doi.org/10.1161/CIR.0000000000000041
- Trends in catheter ablation for atrial fibrillation in the united states.J Hosp Med. 2009; 4 (Available at): E1-E5
- Circumferential pulmonary-vein ablation for chronic atrial fibrillation.N Engl J Med. 2006; 354: 934-941https://doi.org/10.1056/NEJMoa050955
- Ten lifestyle modification approaches to treat atrial fibrillation.Cureus. 2018; 10 (e2682-e2682. Available at)
- Divergent temporal trends in morbidity and mortality related to heart failure and atrial fibrillation: age, sex, race, and geographic differences in the united states, 1991–2015.J Am Heart Assoc. 2019; 8e010756https://doi.org/10.1161/JAHA.118.010756
- Lifetime risk of atrial fibrillation by race and socioeconomic status.Circ Arrhythmia Electrophysiol. 2018; 11e006350https://doi.org/10.1161/CIRCEP.118.006350
- Atrial fibrillation and ethnicity: the known, the unknown and the paradox.Future Cardiol. 2009; 5: 547-556https://doi.org/10.2217/fca.09.49
- Racial differences in atrial fibrillation-related cardiovascular disease and mortality: the atherosclerosis risk in communities (ARIC) studyracial differences in cardiovascular disease and mortalityracial differences in cardiovascular disease and mortalit.JAMA Cardiol. 2016; 1: 433-441https://doi.org/10.1001/jamacardio.2016.1025
- New–onset atrial fibrillation: when is admission medically justified?.Acad Emerg Med. 1996; 3: 114-119https://doi.org/10.1111/j.1553-2712.1996.tb03397.x
- Drivers of hospitalization for patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation (ORBIT-AF).Am Heart J. 2014; 167 (735–42.e2. Available at)
- Estimation of total incremental health care costs in patients with atrial fibrillation in the united states.Circ Cardiovasc Qual Outcomes. 2011; 4: 313-320https://doi.org/10.1161/CIRCOUTCOMES.110.958165
- Contemporary trends of hospitalization for atrial fibrillation in the united states, 2000 through 2010.Circulation. 2014; 129: 2371-2379https://doi.org/10.1161/CIRCULATIONAHA.114.008201
- Economic burden of undiagnosed nonvalvular atrial fibrillation in the united states.Am J Cardiol. 2015; 116: 733-739https://doi.org/10.1016/j.amjcard.2015.05.045
Article info
Publication history
Published online: February 19, 2020
Accepted:
February 3,
2020
Received in revised form:
January 25,
2020
Received:
October 30,
2019
Identification
Copyright
© 2020 Elsevier Inc. All rights reserved.
