Abstract
Introduction
Patients with advanced heart failure (HF) experience many burdensome symptoms that
increase patient suffering.
Methods
Comparative secondary analysis of 347 patients with advanced HF. Symptom burden was
measured with the Memorial Symptom Assessment Scale-HF. Depression was measured using
the Patient Health Questionnaire-9.
Results
Mean number of symptoms was 13.6. The three most frequent symptoms were non-cardiac
pain, shortness of breath, and lack of energy. Patients with depression reported higher
symptom burden. Symptom burden differed when compared by gender. Women reported higher
symptom burden for other pain, dry mouth, swelling of the arms and legs, sweats, feeling
nervous, nausea, and vomiting. Men reported higher symptom burden with sexual problems.
Conclusions
Given the high rates of symptoms and distress, interventions are needed to alleviate
the symptom burden of patients with advanced HF. Reported symptom burden in patients
with advanced heart failure was higher when depressive symptoms were present. Women
reported varied number and severity of symptoms than men.
Keywords
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Article info
Publication history
Published online: March 14, 2019
Accepted:
February 19,
2019
Received in revised form:
January 7,
2019
Received:
August 23,
2018
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.
