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Comparison of the accuracy of three early warning scores with SOFA score for predicting mortality in adult sepsis and septic shock patients admitted to intensive care unit

  • Bodin Khwannimit
    Correspondence
    Corresponding author at: Bodin Khwannimit, Division of Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110 Thailand.
    Affiliations
    Division of Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110 Thailand
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  • Rungsun Bhurayanontachai
    Affiliations
    Division of Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110 Thailand
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  • Veerapong Vattanavanit
    Affiliations
    Division of Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110 Thailand
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      Abstract

      Background

      The purpose of this study was to compare the accuracy of the Modified Early Warning Score (MEWS), National Early Warning Score (NEWS) and Search Out Severity (SOS), with the quick Sequential Organ Failure Assessment (qSOFA) and SOFA scores, to predict outcomes in sepsis patients.

      Methods

      A retrospective study was conducted in intensive care unit of university teaching hospital.

      Results

      A total of 1,589 sepsis patients were enrolled. The SOFA score had the best accuracy to predict hospital mortality, with an area under the receiver operating characteristic curve (AUC) of 0.880 followed by SOS (0.878), MEWS (0.858), qSOFA (0.847) and NEWS (0.833). The SOS score provided a similar performance with SOFA score in predicting mortality.

      Conclusion

      The SOS presents nearly as good as the SOFA score, to predict mortality among sepsis patients admitted to the ICU. The early warning score is another, alternative tool to use for risk stratification and sepsis screening for ICU sepsis patients.

      Keywords

      Abbreviations:

      APACHE (Acute Physiology and Chronic Health Evaluation), AUC (area under the receiver operating characteristic curve), EWS (Early warning scores), ICU (intensive care unit), GCS (Glasgow Coma Score), MEWS (Modified Early Warning Score), NEWS (National Early Warning Score), qSOFA (quick Sequential Organ Failure Assessment), SOS (Search Out Severity), SOFA (Sequential Organ Failure Assessment), SAPS (Simplified Acute Physiology Score), SBP (systolic blood pressure)
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