Objective
Many factors may contribute to medication nonadherence in heart failure (HF), but
no standard measure exists to evaluate factors associated with nonadherence. To fill
this gap, we developed the Medication Adherence Scale (MAS) and tested its reliability
and validity in patients with HF.
Method
Questionnaire data were collected from 100 patients with HF at baseline using the
MAS, and objective adherence data were collected for 3 consecutive months using the
Medication Event Monitoring System.
Results
Principal component analysis yielded three factors that explained 63% of the variance
in medication adherence: knowledge, attitudes, and barriers to medication adherence.
Cronbach's alphas for these subscales ranged from .75 to .94, which supported their
internal consistency. The Spearman rho correlation coefficients between the Medication
Event Monitoring System and Knowledge, Attitudes, and Barriers scores were .25 to
.31 (P < .05), demonstrating support for construct validity.
Conclusion
These results support the reliability and validity of the MAS as a measure of knowledge,
attitudes, and barriers of medication adherence.
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Article info
Footnotes
This study was supported by funding from the Philips Medical-American Association of Critical Care Nurses Outcomes Grant, the National Institute of Health Grant (RO1 NR008567), University of Kentucky General Clinical Research Center (M01RR02602), and Gill Endowment.
Identification
Copyright
© 2008 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
