Heart & Lung: The Journal of Acute and Critical Care
Volume 40, Issue 2 , Pages 172-176, March 2011

Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus

  • Ling Ling Cheung, MBBS

      Affiliations

    • Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong
    • Corresponding Author InformationCorresponding author: Ling Ling Cheung, MBBS, Division of Cardiology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong.
  • ,
  • Chiu Sun Yue, MBBS

      Affiliations

    • Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong
  • ,
  • Kitty Fung, MBBS, MSc

      Affiliations

    • Division of Microbiology, Department of Pathology, United Christian Hospital, Kwun Tong, Hong Kong
  • ,
  • Chung Ming Chu, MBBS, MSc, MD

      Affiliations

    • Division of Respiratory Medicine, United Christian Hospital, Kwun Tong, Hong Kong
  • ,
  • Eugene Yuk Keung Tso, MBBS, MSc

      Affiliations

    • Division of Infectious Diseases, Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong

Received 27 January 2010; received in revised form 18 May 2010; accepted 1 June 2010. published online 30 August 2010.

Abstract 

We report on an intravenous drug user who presented with methicillin-sensitive Staphylococcus aureus bacteremia and endocarditis of a prosthetic tricuspid valve, with a 4-cm vegetation refractory to standard antibiotic treatment. The patient responded to intravenous daptomycin therapy clinically and microbiologically, despite an absence of surgical intervention.

Keywords: Daptomycin, Prosthetic valve endocarditis, Methicillin-sensitive Staphylococcus aureus, Refractory

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 Cite this article: Cheung, L. L., Yue, C. S., Fung, K., Chu, C. M., & Keung Tso, E. Y. (2011, MARCH/APRIL). Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus. Heart & Lung, 40(2), 172-176. doi:10.1016/j.hrtlng.2010.06.002.

PII: S0147-9563(10)00217-7

doi:10.1016/j.hrtlng.2010.06.002

Heart & Lung: The Journal of Acute and Critical Care
Volume 40, Issue 2 , Pages 172-176, March 2011