Risk factors for late extubation after coronary artery bypass grafting

Ji, Qiang; Chi, Liangjie; Mei, Yunqing; Wang, Xisheng; Feng, Jing; Cai, Jiangzhi; Sun, Yifeng

doi:10.1016/j.hrtlng.2009.09.002

« Previous Next »Heart & Lung: The Journal of Acute and Critical Care
Volume 39, Issue 4 , Pages 275-282, July 2010

Risk factors for late extubation after coronary artery bypass grafting

Qiang Ji, MD, PhD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China
Liangjie Chi, PhD
- Medical School of Tongji University, Shanghai, P.R. China
Yunqing Mei, MD, PhD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China
- Corresponding author: Yunqing Mei and Qiang Ji, MD, PhD, Department of Thoraco-Cardiovascular Surgery of Tongji Hospital, Tongji University, 389 Xincun Rd, Shanghai, 200065, P.R. China.
Xisheng Wang, MD, PhD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China
Jing Feng, MD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China
Jiangzhi Cai, MD, PhD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China
Yifeng Sun, MD
- Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China

published online 11 December 2009.

Objective

To evaluate the independent risk factors for late extubation after coronary artery bypass grafting (CABG).

Methods

Preoperative, intraoperative, and postoperative characteristics of patients undergoing isolated CABG between June 2005 and June 2008 at the Tongji Hospital were retrospectively analyzed. Elapsed time between CABG and extubation of more than 8hours was defined as late extubation.

Results

The incidence of late extubation after CABG was 69.23% (288/416). Through univariate and logistic regression analysis, the independent risk factors for late extubation after CABG were older age (odds ratio [OR]=4.804), duration of cardiopulmonary bypass (OR=2.426), perioperative use of intra-aortic balloon pump (OR=1.451), preoperative arterial oxygen partial pressure (OR=.204), and postoperative hemoglobin level (OR=.793).

Conclusion

Older age, prolonged cardiopulmonary bypass time, perioperative intra-aortic balloon pump requirement, low preoperative arterial oxygen partial pressure, and low postoperative hemoglobin level were identified as the 5 independent risk factors for late extubation after CABG.