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Volume 39, Issue 4, Pages 275-282 (July 2010)


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Risk factors for late extubation after coronary artery bypass grafting

Qiang Ji, MD, PhDaemail address, Liangjie Chi, PhDb, Yunqing Mei, MD, PhDaCorresponding Author Informationemail address, Xisheng Wang, MD, PhDa, Jing Feng, MDa, Jiangzhi Cai, MD, PhDa, Yifeng Sun, MDa

published online 11 December 2009.

Objective

To evaluate the independent risk factors for late extubation after coronary artery bypass grafting (CABG).

Methods

Preoperative, intraoperative, and postoperative characteristics of patients undergoing isolated CABG between June 2005 and June 2008 at the Tongji Hospital were retrospectively analyzed. Elapsed time between CABG and extubation of more than 8hours was defined as late extubation.

Results

The incidence of late extubation after CABG was 69.23% (288/416). Through univariate and logistic regression analysis, the independent risk factors for late extubation after CABG were older age (odds ratio [OR]=4.804), duration of cardiopulmonary bypass (OR=2.426), perioperative use of intra-aortic balloon pump (OR=1.451), preoperative arterial oxygen partial pressure (OR=.204), and postoperative hemoglobin level (OR=.793).

Conclusion

Older age, prolonged cardiopulmonary bypass time, perioperative intra-aortic balloon pump requirement, low preoperative arterial oxygen partial pressure, and low postoperative hemoglobin level were identified as the 5 independent risk factors for late extubation after CABG.

a Department of Thoracic Cardiovascular Surgery of Tongji Hospital of Tongji University, Shanghai, P.R. China

b Medical School of Tongji University, Shanghai, P.R. China

Corresponding Author InformationCorresponding author: Yunqing Mei and Qiang Ji, MD, PhD, Department of Thoraco-Cardiovascular Surgery of Tongji Hospital, Tongji University, 389 Xincun Rd, Shanghai, 200065, P.R. China.

PII: S0147-9563(09)00232-5

doi:10.1016/j.hrtlng.2009.09.002


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