Heart & Lung: The Journal of Acute and Critical Care
Volume 39, Issue 3 , Pages 237-239, May 2010

Successful treatment of saphenous venous graft thrombus by tirofiban infusion

Department of Cardiology, School of Medicine, Uludag University, Görükle, Bursa, Turkey

published online 16 October 2009.

A 60-year old man with a history of coronary-artery bypass grafting presented with symptoms of acute coronary syndrome. Coronary angiography revealed a huge intraluminal thrombus in the saphenous vein graft to the second obtuse marginal branch of the left circumflex artery. A glycoprotein IIb/IIIa inhibitor (tirofiban) was administered intravenously. Two days later, thrombus dissolution and Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow were evident on repeat coronary angiography. Glycoprotein IIb/IIIa inhibitors may be useful in a thrombus-laden saphenous-vein graft.

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PII: S0147-9563(09)00183-6

doi:10.1016/j.hrtlng.2009.07.001

Heart & Lung: The Journal of Acute and Critical Care
Volume 39, Issue 3 , Pages 237-239, May 2010