Heart & Lung: The Journal of Acute and Critical Care
Volume 39, Issue 2 , Pages 160-163 , March 2010

Severe myocardial ischemia after concentrated epinephrine use for the treatment of anaphylaxis: Kounis syndrome or epinephrine effect?

  • Cemil Izgi, MD

      Affiliations

    • Ozel Gaziosmanpasa Hospital, Division of Cardiology, Istanbul, Turkey
    • ,
  • Cihan Cevik, MD

      Affiliations

    • Texas Tech University Health Sciences Center, Department of Internal Medicine, Lubbock, Texas
    • Corresponding Author InformationReprint requests: Cihan Cevik, MD, Texas Tech University Health Sciences Center, Department of Internal Medicine, 3601 4th Street, Lubbock, TX 79430.
    • ,
  • Kenneth Nugent, MD

      Affiliations

    • Texas Tech University Health Sciences Center, Department of Internal Medicine, Lubbock, Texas

References 

  1. Kounis NG, Zavras GM. Histamine-induced coronary artery spasm: the concept of allergic angina. Br J Clin Pract. 1991;45:121–128
  2. Ridella M, Bagdure S, Nugent K, Cevik C. Kounis syndrome following beta-lactam antibiotic use: review of literature. Inflamm Allergy Drug Targets. 2009;8:11–16
  3. Abraham J, Mudd JO, Kapur N, Klein K, Champion HC, Wittstein IS. Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. J Am Coll Cardiol. 2009;53:1320–1325
  4. Takagi S, Goto Y, Hirose E, et al. Successful treatment of refractory vasospastic angina with corticosteroids: coronary arterial hyperactivity caused by local inflammation?. Circ J. 2004;68:17–22
  5. Lieberman P, Kemp SF, Oppenheimer J, et al. Joint Task Force on Practice Parameters. The diagnosis and management of anaphylaxis: an updated practice parameter. J Allergy Clin Immunol. 2005;115:S483–S523
  6. Kemp SF, Lockey RF, Simons FE World Allergy Organization ad hoc Committee on Epinephrine in Anaphylaxis. Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization. Allergy. 2008;63:1061–1070
  7. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:239–245

 Conflict of Interest: None.

PII: S0147-9563(09)00159-9

doi: 10.1016/j.hrtlng.2009.06.012

Heart & Lung: The Journal of Acute and Critical Care
Volume 39, Issue 2 , Pages 160-163 , March 2010

Article Tools

* Image Usage & Resolution