Heart & Lung: The Journal of Acute and Critical Care
Volume 38, Issue 6 , Pages 526-529, November 2009

Herpes simplex virus type-1 pneumonitis in immunocompetent young woman

  • Cesar V. Reyes, MD

      Affiliations

    • Department of Clinical Laboratories, Morris Hospital, Morris, Illinois
    • Corresponding Author InformationCorresponding author: Cesar V. Reyes, MD, 6530 Dunham Road, Downers Grove, IL 60516
  • ,
  • John R. Bolden, MD

      Affiliations

    • Section of Infectious Diseases, Morris Hospital, Morris, Illinois

published online 14 July 2009.

Abstract 

A healthy young woman presented with an overwhelming hyperacute herpes simplex virus-1 pneumonia that dramatically responded to intravenous acyclovir. It is postulated that the infection was a reactivation of latent virus in the vagal ganglia, in the absence of retrograde extension of herpes labialis/gingivostomatitis, or hematogenous spread from extragenital and other sources of infection. It is also postulated that the patient's amazing improvement overnight was a real-time coincidence of spontaneous recovery from the viral infection and prompt initiation of acyclovir treatment.

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PII: S0147-9563(09)00131-9

doi:10.1016/j.hrtlng.2009.05.002

Heart & Lung: The Journal of Acute and Critical Care
Volume 38, Issue 6 , Pages 526-529, November 2009