Heart & Lung: The Journal of Acute and Critical Care
Volume 35, Issue 6 , Pages 363-373 , November 2006

Prevalence of myocardial ischemia during mechanical ventilation and weaning and its effects on weaning success

  • Susan K. Frazier, PhD, RN

      Affiliations

    • College of Nursing, University of Kentucky, Lexington, Kentucky
    • Corresponding Author InformationReprint requests: Susan K. Frazier, PhD, RN, 523 CON Bldg., College of Nursing, University of Kentucky, Lexington, KY 40536-5791.
    • ,
  • Heather Brom, BS, RN

      Affiliations

    • College of Nursing, The Ohio State University, Columbus, Ohio.
    • ,
  • Jeanne Widener, MS, RN

      Affiliations

    • College of Nursing, The Ohio State University, Columbus, Ohio.
    • ,
  • Lauren Pender, BSN, RN

      Affiliations

    • College of Nursing, The Ohio State University, Columbus, Ohio.
    • ,
  • Kathleen S. Stone, PhD, RN, FAAN

      Affiliations

    • College of Nursing, The Ohio State University, Columbus, Ohio.
    • ,
  • Debra K. Moser, DNSc, RN, FAAN

      Affiliations

    • College of Nursing, The Ohio State University, Columbus, Ohio.

References 

  1. Jacobs P, Edbrooke D, Hibbert C, Fassbender K, Corcoran M. Descriptive patient data as an explanation for the variation in average daily costs in intensive care. Anaesthesia. 2001;56:643–647
  2. Tonnelier J, Prat G, Le Gal G, Gut-Gobert C, Renault A, Boles J, et al. Impact of a nurses’ protocol-directed weaning procedure on outcomes in patients undergoing mechanical ventilation for longer than 48 hours: a prospective cohort study with a matched historical control group. Crit Care. 2005;9:R83–R89
  3. American Association for Respiratory Care. A study of chronic ventilator patients in the hospital. Dallas, TX: American Association for Respiratory Care; 1991;
  4. Demling R, Read T, Lind L, Flanagan H. Incidence and morbidity of extubation failure in surgical intensive care patients. Crit Care Med. 1988;16:573–577
  5. Clochesy J, Daly B, Montenegro H. Weaning chronically critically ill adults from mechanical ventilatory support: a descriptive study. Am J Crit Care. 1995;4:93–99
  6. Teboul J, Abrouk F, Lemaire F. Right ventricular function in COPD patients during weaning from mechanical ventilation. Intensive Care Med. 1988;14:483–485
  7. Sereika S, Clochesy J. Left ventricular dysfunction and duration of mechanical ventilatory support in the chronically critically ill: a survival analysis. Heart Lung. 1996;25:45–51
  8. Hurford W, Lynch K, Strauss H, Lowenstein E, Zapol W. Myocardial perfusion as assessed by thallium-201 scintigraphy during the discontinuation of mechanical ventilation in ventilator-dependent patients. Anesthesiology. 1991;74:1007–1016
  9. Elia S, Liu P, Hilgenberg A, Skourtis C, Lappas D. Coronary haemodynamics and myocardial metabolism during weaning from mechanical ventilation in cardiac surgical patients. Can J Anaesth. 1991;38:564–571
  10. Abalos A, Leibowitz A, Distefano D, Halpern N, Iberti T. Myocardial ischemia during the weaning period. Am J Crit Care. 1992;3:32–36
  11. Hurford W, Favorito F. Association of myocardial ischemia with failure to wean from mechanical ventilation. Crit Care Med. 1995;23:1475–1480
  12. Chatila W, Ani S, Guaglianone D, Jacob B, Amoateng-Adjepong Y, Manthous C. Cardiac ischemia during weaning from mechanical ventilation. Chest. 1996;109:1577–1583
  13. Srivastava S, Chatila W, Amoateng-Adjepong Y, Kanagasegar S, Jacob B, Zarich S, et al. Myocardial ischemia and weaning failure in patients with coronary artery disease: an update. Crit Care Med. 1999;27:2109–2112
  14. Fewell J, Abenschein D, Carlson C, Rapaport E, Murray J. Mechanism of decreased right and left ventricular end-diastolic volumes during continuous positive-pressure ventilation in dogs. Circ Res. 1980;47:467–472
  15. Fewell J, Abendschein D, Carlson C, Murray J, Rapaport E. Continuous positive end-expiratory pressure ventilation decreases right and left ventricular end-diastolic volumes in the dog. Circ Res. 1980;46:125–132
  16. Viquerat C, Righetti A, Suter P. Biventricular volumes and function in patients with adult respiratory distress syndrome ventilated with PEEP. Chest. 1983;83:509–514
  17. Dhainaut J, Devaux J, Monsallier J, Brunet F, Villemant D, Huyghebaert M. Mechanisms of decreased left ventricular preload during continuous positive pressure ventilation in ARDS. Chest. 1986;90:74–80
  18. Potkin R, Hudson L, Weaver L, Trobaugh G. Effect of positive end-expiratory pressure on right and left ventricular function in patients with adult respiratory distress syndrome. Am Rev Respir Dis. 1987;135:307–311
  19. Frazier SK, Stone KS, Schertel ER, Moser DK, Pratt J. A comparison of hemodynamic changes during the transition from mechanical ventilation to T-piece, pressure support and continuous positive airway pressure in canines. Bio Res Nurs. 2000;1:253–264
  20. Frazier SK, Moser DK, Stone KS. Cardiac power output during transition from mechanical to spontaneous ventilation in canines. J Cardiovasc Nurs. 2001;15:23–32
  21. Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular performance (Importance of baseline right ventricular function). Am J Med. 1988;84:57–67
  22. Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular pressure. Am Rev Respir Dis. 1990;141:1531–1537
  23. Johnston W, Vinten-Johansen J, Shugart H, Santamore W. Positive end-expiratory pressure potentiates the severity of canine right ventricular ischemia-reperfusion injury Am J Physiol. 1992;262:H168–H176
  24. Brienza A, Dambrosio M, Bruno F, Lagioia V, Marucci M, Belpiede G, et al. Right ventricular ejection fraction measurement in moderate acute respiratory failure (ARF) (Effects of PEEP). Intensive Care Med. 1988;14:478–482
  25. Neidhart P, Suter P. Changes in right ventricular function with positive end-expiratory pressure (PEEP) in man. Intensive Care Med. 1988;14:471–473
  26. Kim LJ, Martinez EA, Faraday N, Dorman T, Fleisher LA, Perley BA, et al. Cardiac troponin-I predicts short-term mortality in vascular surgery patients. Circulation. 2002;106:2366–2371
  27. Ammann P, Maggiorini M, Bertel O, Haenseler E, Joller-Jemelka HI, Oechslin E, et al. Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes. J Am Coll Cardiol. 2003;41:2004–2009
  28. Horwich TB, Patel J, MacLellan R, Fonarow GC. Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction, and increased mortality rates in advanced heart failure. Circulation. 2003;108:833–838
  29. Landesberg G, Vesselov Y, Einav S, Goodman S, Sprung CL, Weissman C. Myocardial ischemia, cardiac troponin, and long-term survival of high-cardiac risk critically ill intensive care unit patients. Crit Care Med. 2005;33:1281–1287
  30. Patton JA, Funk M. Survey of use of ST-segment monitoring in patients with acute coronary syndromes. Am J Crit Care. 2001;10:23–32

 Supported by National Institutes of Health National Institute of Nursing Research Grant No. 1 R15 NR05059-01; Agilent Technologies-American Association of Colleges of Nursing Research Grant; and General Clinical Research Center Grant No. M01 RR00034.

PII: S0147-9563(06)00005-7

doi: 10.1016/j.hrtlng.2005.12.006

Heart & Lung: The Journal of Acute and Critical Care
Volume 35, Issue 6 , Pages 363-373 , November 2006

Article Tools

* Image Usage & Resolution